NeuroStar TMS Therapy® — Help Your Patients Reach Remission and Stay There

NeuroStar is the only TMS treatment with demonstrated durability in depression over 1 year20


Read more about the proven short- and long-term efficacy of NeuroStar TMS Therapy for patients with major depressive disorder:

Significant response was maintained 12 months after acute depression treatment20

In a naturalistic clinical study in 257 patients who did not benefit from antidepressant medications, NeuroStar TMS Therapy offered durable effect over 1 year following acute treatment:

  • 67.7% of patients responded to treatment
  • 45.1% reached remission

36.2% of patients received NeuroStar TMS Therapy reintroduction (average of 16 treatments). Long-term durability of effect has not been established in a randomized trial. Trial design used physician-directed standard of care.

In acute phase of treatment, 1 in 2 patients responded to therapy and 1 in 3 reached remission6

  • Consistent response and remission rates across a broad range of antidepressant treatment resistance6
    • Patients with both low and high treatment-resistant depression who are treated with NeuroStar TMS Therapy experience significant benefits after 4 to 6 weeks of treatment.

CGI-S outcomes in acute phase of treatment

NeuroStar end of acute treatment outcomes

An open-label, multicenter study included 307 (acute phase) evaluable, unipolar, non-psychotic MDD patients in post-market use who were evaluated after treatment with NeuroStar TMS Therapy.6

View NeuroStar TMS Therapy safety data

Clinical results demonstrated an improvement in depression symptoms

  • In an NIMH-funded, independent, randomized, controlled trial, patients treated with TMS using the NeuroStar TMS System were four times more likely to achieve remission compared to patients receiving sham treatment (P=0.0173; odds ratio=4.05)8
  • Significant improvement from baseline with NeuroStar TMS Therapy was observed as early as 2 weeks after treatment and at 4 and 6 weeks (P=0.0006)5

NeuroStar TMS Therapy is backed by the largest clinical data set of any TMS system

  • Two multisite, randomized, controlled trials demonstrated the clinically significant antidepressant effect of NeuroStar TMS Therapy7,8
  • Two open-label extension studies similarly demonstrated benefit5,9
  • One prospective, naturalistic study confirmed results in real-world practice6
  • Two open-label, long-term, follow-up studies10,19

Ongoing Clinical Trials

Neuronetics continues to support clinical trial programs. The following are sponsored by Neuronetics:

Adolescent Depression Study

Other studies using NeuroStar/Neuronetics devices

If you are interested in conducting an Investigator Initiated Trial, please contact Neuronetics Customer Service at
1-877-600-7555 (option 3).